BDBM50005836 4-Amino-5-chloro-N-{1-[3-(4-fluoro-phenoxy)-propyl]-3-methoxy-piperidin-4-yl}-2-methoxy-benzamide::4-amino-5-chloro-N-(1-(3-(4-fluorophenoxy)propyl)-3-methoxypiperidin-4-yl)-2-methoxybenzamide::CHEMBL560739::CISAPRIDE::PROPULSID::US10167299, Cisapride::US10800776, Example Cisapride::US9221790, Cisapride::cid_5311047
SMILES COC1CN(CCCOc2ccc(F)cc2)CCC1NC(=O)c1cc(Cl)c(N)cc1OC
InChI Key InChIKey=DCSUBABJRXZOMT-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 17 hits for monomerid = 50005836
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Tcg Lifesciences
Curated by ChEMBL
Tcg Lifesciences
Curated by ChEMBL
Affinity DataIC50: 6.76nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Tcg Lifesciences
Curated by ChEMBL
Tcg Lifesciences
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of human ERG expressed in CHO cells assessed as whole cell current by patch clamp assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Tcg Lifesciences
Curated by ChEMBL
Tcg Lifesciences
Curated by ChEMBL
Affinity DataIC50: 6.5nMAssay Description:Inhibition of hERG K channelMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Tcg Lifesciences
Curated by ChEMBL
Tcg Lifesciences
Curated by ChEMBL
Affinity DataIC50: 98nMAssay Description:Inhibition of human ERG overexpressed in CHO cells by Qpatch methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Tcg Lifesciences
Curated by ChEMBL
Tcg Lifesciences
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of human Potassium channel HERG expressed in mammalian cellsMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Tcg Lifesciences
Curated by ChEMBL
Tcg Lifesciences
Curated by ChEMBL
Affinity DataIC50: 45nMAssay Description:Inhibition of K+ channel activity in CHO cells expressing HERG Kv11.1More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Tcg Lifesciences
Curated by ChEMBL
Tcg Lifesciences
Curated by ChEMBL
Affinity DataIC50: 47nMAssay Description:Inhibitory activity against Potassium channel HERGMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Tcg Lifesciences
Curated by ChEMBL
Tcg Lifesciences
Curated by ChEMBL
Affinity DataIC50: 6.5nMAssay Description:K+ channel blocking activity in human embryonic kidney cells expressing HERG Kv11.1More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Tcg Lifesciences
Curated by ChEMBL
Tcg Lifesciences
Curated by ChEMBL
Affinity DataIC50: 6.5nMAssay Description:Inhibition of partially open human voltage-gated potassium channel subunit Kv11.1 (ERG K+ channel)More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Tcg Lifesciences
Curated by ChEMBL
Tcg Lifesciences
Curated by ChEMBL
Affinity DataIC50: 6.70nMAssay Description:Inhibition of human ERG channelMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Tcg Lifesciences
Curated by ChEMBL
Tcg Lifesciences
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of wild-type human ERG expressed in HEK293 cells by whole cell patch clamp methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Tcg Lifesciences
Curated by ChEMBL
Tcg Lifesciences
Curated by ChEMBL
Affinity DataIC50: 6.46nMAssay Description:Inhibition of human ERG in MCF7 cellsMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Tcg Lifesciences
Curated by ChEMBL
Tcg Lifesciences
Curated by ChEMBL
Affinity DataIC50: 39.8nMAssay Description:Inhibitory concentration against potassium channel HERGMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Tcg Lifesciences
Curated by ChEMBL
Tcg Lifesciences
Curated by ChEMBL
Affinity DataIC50: 39.8nMAssay Description:Inhibition of human ERG expressed in CHO cells by whole cell patch clamp techniqueMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Tcg Lifesciences
Curated by ChEMBL
Tcg Lifesciences
Curated by ChEMBL
Affinity DataIC50: 190nMAssay Description:1. CHO-hERG cells which have been incubated overnight were added with sample buffer and incubated for 90 minutes at room temperature in darkness.2. T...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Tcg Lifesciences
Curated by ChEMBL
Tcg Lifesciences
Curated by ChEMBL
Affinity DataIC50: 130nMAssay Description:Experimental method: hERG patch clamp detection methodExperimental procedure: Compound preparation: the stock solution of a compound was diluted with...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Tcg Lifesciences
Curated by ChEMBL
Tcg Lifesciences
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of hERG potassium channel assessed as maximum inhibition rate at -80 mV holding potential incubated for 120 seconds by whole cell-automate...More data for this Ligand-Target Pair